The potential utility of native tissue fluorescence spectroscopy for in vivo cancer detection in humans was first discovered by Professor Robert R. Alfano, Distinguished Professor of Physics and Engineering at the City College of the City University of New York (CUNY).

Mediscience Technology, CUNY, and the Research Foundation of CUNY established the Mediphotonics Laboratory (MPL) at CUNY to provide research and development services in the area of tissue spectroscopy, cancer detection, and other biological applications.

The staff of MPL, supervised by Dr. Alfano, developed our current CD prototype devices. MPL was instrumental in developing our company's latest technological breakthrough in medical imaging, the Stokes Shift Emission Spectroscopy method. When comparing the effectiveness of the Stokes Shift Emission Spectroscopy (SS) method with conventional fluorescence spectroscopy, it is emphatically clear that the SS method is significantly more selective, providing a more effective means of distinguishing cancerous from normal tissue.

MPL also piloted in vitro, pre-clinical testing of various human tissue types such as breast, cervical, colon, and the upper aerodigestive tract. The goal was to develop the preferred optical scanning and emission wavelengths that yield the most definitive information about the native fluorescence characteristics of specific scanned tissue.

The insight gained from this research has been the principal source of knowledge for the company's subsequently issued and pending patents. These patents are either owned outright or components of the company's worldwide exclusive license, highly regarded as pioneering, blocking, and dominant in the area of cancer diagnosis using fluorescence.

Moreover, numerous scientific papers published in peer-review journals and scientific symposia presentations were derived from the research.

Finally, the MPL in vitro preclinical research and development provided the foundation for Mediscience Technology's optical scanning parameters for in vivo human clinical studies.